Obstructive sleep apnea (OSA), a prevalent disorder characterized by recurrent upper airway collapse, is increasingly recognized as a systemic inflammatory condition influenced by microbial dysregulation. Emerging evidence underscores the role of the lung microbiome as a mediator in the pathophysiology of OSA, where dysbiotic changes driven by intermittent hypoxia, oxidative stress, and mechanical airway trauma amplify inflammatory cascades and perpetuate respiratory instability. This review synthesizes current knowledge on the bidirectional interaction between OSA and lung microbial communities.
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Link: https://www.mdpi.com/2075-4418/15/11/1431
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