{"id":63840,"date":"2026-07-20T16:30:05","date_gmt":"2026-07-20T14:30:05","guid":{"rendered":"https:\/\/carlosoconnor.es\/?p=63840"},"modified":"2026-07-20T16:33:40","modified_gmt":"2026-07-20T14:33:40","slug":"alternativas-farmacologicas-en-estudio-para-el-tratamiento-de-aos","status":"publish","type":"post","link":"https:\/\/carlosoconnor.es\/en\/alternativas-farmacologicas-en-estudio-para-el-tratamiento-de-aos\/","title":{"rendered":"Alternativas farmacol\u00f3gicas en estudio para el tratamiento de AOS"},"content":{"rendered":"

En la actualidad hay avances que buscan dianas terap\u00e9uticas personalizadas m\u00e1s all\u00e1 del tradicional CPAP. Por eso, sigo con mucha atenci\u00f3n los resultados del ensayo cl\u00ednico SynAIRgy, que analiza el AD109 (una combinaci\u00f3n de aroxybutynina y atomoxetina) dise\u00f1ado espec\u00edficamente para mejorar la respuesta neuromuscular de los m\u00fasculos dilatadores y reducir el colapso de la v\u00eda a\u00e9rea en pacientes con apnea obstructiva del sue\u00f1o (AOS) leve a moderada. Aunque este abordaje farmacol\u00f3gico logr\u00f3 disminuir el \u00edndice de apnea-hipopnea (IAH) y atenuar los ronquidos, nos enfrenta a un gran desaf\u00edo de adherencia: un 21.2% de los pacientes abandon\u00f3 el tratamiento debido a efectos adversos como boca seca, insomnio y problemas urinarios, adem\u00e1s de registrarse peque\u00f1os incrementos en la presi\u00f3n arterial. Estos resultados refuerzan profundamente mi convicci\u00f3n de que, si el prop\u00f3sito principal es restaurar de manera dirigida el tono y la activaci\u00f3n de la musculatura de la v\u00eda a\u00e9rea superior, la terapia miofuncional se consolida como la alternativa no invasiva por excelencia; al ejercitar activamente los m\u00fasculos far\u00edngeos y linguales, logramos ese mismo objetivo funcional de forma totalmente natural, segura y sin el riesgo de efectos secundarios sist\u00e9micos.<\/p>\n\n\n\n

Enlace de referencia: https:\/\/academic.oup.com\/ajrccm\/article\/212\/7\/1427\/8679096?login=false<\/a><\/p>\n\n\n\n

#MedicinaDelSue\u00f1o #Otorrinolaringolog\u00eda #ApneaDelSue\u00f1o #TerapiaMiofuncional #FarmacoterapiaSue\u00f1o #SynAIRgy #SaludIntegral #DescansoSaludable #AlternativasAlCPAP #Fisiolog\u00edaDelSue\u00f1o<\/p>\n\n\n\n

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En la actualidad hay avances que buscan dianas terap\u00e9uticas personalizadas m\u00e1s all\u00e1 del tradicional CPAP. Por eso, sigo con mucha atenci\u00f3n los resultados del ensayo cl\u00ednico SynAIRgy, que analiza el…<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-63840","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"\nAlternativas farmacol\u00f3gicas en estudio para el tratamiento de AOS - Carlos O'Connor<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/carlosoconnor.es\/en\/alternativas-farmacologicas-en-estudio-para-el-tratamiento-de-aos\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Alternativas farmacol\u00f3gicas en estudio para el tratamiento de AOS - Carlos O'Connor\" \/>\n<meta property=\"og:description\" content=\"En la actualidad hay avances que buscan dianas terap\u00e9uticas personalizadas m\u00e1s all\u00e1 del tradicional CPAP. 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