{"id":63535,"date":"2026-06-05T18:44:02","date_gmt":"2026-06-05T16:44:02","guid":{"rendered":"https:\/\/carlosoconnor.es\/?p=63535"},"modified":"2026-06-05T18:44:09","modified_gmt":"2026-06-05T16:44:09","slug":"la-hipoxia-y-el-cancer","status":"publish","type":"post","link":"https:\/\/carlosoconnor.es\/en\/la-hipoxia-y-el-cancer\/","title":{"rendered":"La hipoxia y el c\u00e1ncer"},"content":{"rendered":"

La hipoxia es un motor cr\u00edtico en la progresi\u00f3n del c\u00e1ncer, la evasi\u00f3n inmunitaria y la resistencia a los tratamientos antitumorales. Tradicionalmente se ha considerado un fen\u00f3meno exclusivo e intr\u00ednseco del microambiente tumoral. Sin embargo, una reciente revisi\u00f3n narrativa aporta una evidencia cient\u00edfica disruptiva: la hipoxia intermitente cr\u00f3nica ocurrida durante el sue\u00f1o act\u00faa como un catalizador sist\u00e9mico y modificable de las v\u00edas oncog\u00e9nicas.<\/p>\n\n\n\n

Este estudio demuestra que la normoxia nocturna es un objetivo biol\u00f3gicamente significativo y cl\u00ednicamente accionable. Como especialistas en medicina del sue\u00f1o, estos hallazgos abren una v\u00eda de colaboraci\u00f3n directa e hist\u00f3rica con los servicios de oncolog\u00eda. Tratar eficazmente los trastornos respiratorios del sue\u00f1o en pacientes oncol\u00f3gicos ya no es solo una medida para mejorar su calidad de vida y descanso; es una intervenci\u00f3n biol\u00f3gica activa destinada a derribar las barreras de la resistencia a las terapias contra el c\u00e1ncer y mejorar dr\u00e1sticamente sus resultados cl\u00ednicos.<\/p>\n\n\n\n

Referencia del estudio comentado: https:\/\/www.dovepress.com\/restoring-physiological-normoxia-as-an-adjuvant-strategy-to-improve-ca-peer-reviewed-fulltext-article-NS<\/a><\/p>\n\n\n\n

#OSAeducation<\/strong> #SleepApnea<\/strong> #Oncolog\u00eda<\/strong> #HipoxiaIntermitente<\/strong> #NormoxiaNocturna<\/strong> #CPAP<\/strong> #MicroambienteTumoral<\/strong> #Inmunoterapia<\/strong> #MedicinaTraslacional<\/strong> #MedicinaMultidisciplinar<\/strong> #SleepMedicine<\/strong><\/p>\n\n\n\n

\"images
images 2026 06 05T111258.629<\/figcaption><\/figure>","protected":false},"excerpt":{"rendered":"

La hipoxia es un motor cr\u00edtico en la progresi\u00f3n del c\u00e1ncer, la evasi\u00f3n inmunitaria y la resistencia a los tratamientos antitumorales. Tradicionalmente se ha considerado un fen\u00f3meno exclusivo e intr\u00ednseco…<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-63535","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"\nLa hipoxia y el c\u00e1ncer - Carlos O'Connor<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/carlosoconnor.es\/en\/la-hipoxia-y-el-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"La hipoxia y el c\u00e1ncer - Carlos O'Connor\" \/>\n<meta property=\"og:description\" content=\"La hipoxia es un motor cr\u00edtico en la progresi\u00f3n del c\u00e1ncer, la evasi\u00f3n inmunitaria y la resistencia a los tratamientos antitumorales. Tradicionalmente se ha considerado un fen\u00f3meno exclusivo e intr\u00ednseco…\" \/>\n<meta property=\"og:url\" content=\"https:\/\/carlosoconnor.es\/en\/la-hipoxia-y-el-cancer\/\" \/>\n<meta property=\"og:site_name\" content=\"Carlos O'Connor\" \/>\n<meta property=\"article:published_time\" content=\"2026-06-05T16:44:02+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-06-05T16:44:09+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/carlosoconnor.es\/wp-content\/uploads\/2026\/06\/images-2026-06-05T111258.629.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"306\" \/>\n\t<meta property=\"og:image:height\" content=\"165\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"gestion\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"gestion\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/\"},\"author\":{\"name\":\"gestion\",\"@id\":\"https:\/\/carlosoconnor.es\/#\/schema\/person\/c879dbc2b732eaa32429f50dfbd0a949\"},\"headline\":\"La hipoxia y el c\u00e1ncer\",\"datePublished\":\"2026-06-05T16:44:02+00:00\",\"dateModified\":\"2026-06-05T16:44:09+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/\"},\"wordCount\":207,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/carlosoconnor.es\/#organization\"},\"image\":{\"@id\":\"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/carlosoconnor.es\/wp-content\/uploads\/2026\/06\/images-2026-06-05T111258.629.jpg\",\"articleSection\":[\"Uncategorized\"],\"inLanguage\":\"en-GB\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/\",\"url\":\"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/\",\"name\":\"La hipoxia y el c\u00e1ncer - Carlos O'Connor\",\"isPartOf\":{\"@id\":\"https:\/\/carlosoconnor.es\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/carlosoconnor.es\/wp-content\/uploads\/2026\/06\/images-2026-06-05T111258.629.jpg\",\"datePublished\":\"2026-06-05T16:44:02+00:00\",\"dateModified\":\"2026-06-05T16:44:09+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/#breadcrumb\"},\"inLanguage\":\"en-GB\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/#primaryimage\",\"url\":\"https:\/\/carlosoconnor.es\/wp-content\/uploads\/2026\/06\/images-2026-06-05T111258.629.jpg\",\"contentUrl\":\"https:\/\/carlosoconnor.es\/wp-content\/uploads\/2026\/06\/images-2026-06-05T111258.629.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Portada\",\"item\":\"https:\/\/carlosoconnor.es\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"La hipoxia y el c\u00e1ncer\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/carlosoconnor.es\/#website\",\"url\":\"https:\/\/carlosoconnor.es\/\",\"name\":\"Carlos O'Connor\",\"description\":\"Dr. Carlos O'Connor Reina - Otorrinolaring\u00f3logo\",\"publisher\":{\"@id\":\"https:\/\/carlosoconnor.es\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/carlosoconnor.es\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-GB\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/carlosoconnor.es\/#organization\",\"name\":\"Carlos O'Connor\",\"url\":\"https:\/\/carlosoconnor.es\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\/\/carlosoconnor.es\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/carlosoconnor.es\/wp-content\/uploads\/2025\/07\/cropped-logo-wide.png\",\"contentUrl\":\"https:\/\/carlosoconnor.es\/wp-content\/uploads\/2025\/07\/cropped-logo-wide.png\",\"width\":241,\"height\":50,\"caption\":\"Carlos O'Connor\"},\"image\":{\"@id\":\"https:\/\/carlosoconnor.es\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/carlosoconnor.es\/#\/schema\/person\/c879dbc2b732eaa32429f50dfbd0a949\",\"name\":\"gestion\",\"sameAs\":[\"https:\/\/www.ycomieronperdices.net\/temp\/oconnor2025\"],\"url\":\"https:\/\/carlosoconnor.es\/en\/author\/gestion\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"La hipoxia y el c\u00e1ncer - Carlos O'Connor","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/carlosoconnor.es\/en\/la-hipoxia-y-el-cancer\/","og_locale":"en_GB","og_type":"article","og_title":"La hipoxia y el c\u00e1ncer - Carlos O'Connor","og_description":"La hipoxia es un motor cr\u00edtico en la progresi\u00f3n del c\u00e1ncer, la evasi\u00f3n inmunitaria y la resistencia a los tratamientos antitumorales. Tradicionalmente se ha considerado un fen\u00f3meno exclusivo e intr\u00ednseco…","og_url":"https:\/\/carlosoconnor.es\/en\/la-hipoxia-y-el-cancer\/","og_site_name":"Carlos O'Connor","article_published_time":"2026-06-05T16:44:02+00:00","article_modified_time":"2026-06-05T16:44:09+00:00","og_image":[{"width":306,"height":165,"url":"https:\/\/carlosoconnor.es\/wp-content\/uploads\/2026\/06\/images-2026-06-05T111258.629.jpg","type":"image\/jpeg"}],"author":"gestion","twitter_card":"summary_large_image","twitter_misc":{"Written by":"gestion","Estimated reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/#article","isPartOf":{"@id":"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/"},"author":{"name":"gestion","@id":"https:\/\/carlosoconnor.es\/#\/schema\/person\/c879dbc2b732eaa32429f50dfbd0a949"},"headline":"La hipoxia y el c\u00e1ncer","datePublished":"2026-06-05T16:44:02+00:00","dateModified":"2026-06-05T16:44:09+00:00","mainEntityOfPage":{"@id":"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/"},"wordCount":207,"commentCount":0,"publisher":{"@id":"https:\/\/carlosoconnor.es\/#organization"},"image":{"@id":"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/#primaryimage"},"thumbnailUrl":"https:\/\/carlosoconnor.es\/wp-content\/uploads\/2026\/06\/images-2026-06-05T111258.629.jpg","articleSection":["Uncategorized"],"inLanguage":"en-GB","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/","url":"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/","name":"La hipoxia y el c\u00e1ncer - Carlos O'Connor","isPartOf":{"@id":"https:\/\/carlosoconnor.es\/#website"},"primaryImageOfPage":{"@id":"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/#primaryimage"},"image":{"@id":"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/#primaryimage"},"thumbnailUrl":"https:\/\/carlosoconnor.es\/wp-content\/uploads\/2026\/06\/images-2026-06-05T111258.629.jpg","datePublished":"2026-06-05T16:44:02+00:00","dateModified":"2026-06-05T16:44:09+00:00","breadcrumb":{"@id":"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/#breadcrumb"},"inLanguage":"en-GB","potentialAction":[{"@type":"ReadAction","target":["https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/"]}]},{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/#primaryimage","url":"https:\/\/carlosoconnor.es\/wp-content\/uploads\/2026\/06\/images-2026-06-05T111258.629.jpg","contentUrl":"https:\/\/carlosoconnor.es\/wp-content\/uploads\/2026\/06\/images-2026-06-05T111258.629.jpg"},{"@type":"BreadcrumbList","@id":"https:\/\/carlosoconnor.es\/la-hipoxia-y-el-cancer\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Portada","item":"https:\/\/carlosoconnor.es\/"},{"@type":"ListItem","position":2,"name":"La hipoxia y el c\u00e1ncer"}]},{"@type":"WebSite","@id":"https:\/\/carlosoconnor.es\/#website","url":"https:\/\/carlosoconnor.es\/","name":"Carlos O'Connor","description":"Dr. Carlos O'Connor Reina - Otorrinolaring\u00f3logo","publisher":{"@id":"https:\/\/carlosoconnor.es\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/carlosoconnor.es\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-GB"},{"@type":"Organization","@id":"https:\/\/carlosoconnor.es\/#organization","name":"Carlos O'Connor","url":"https:\/\/carlosoconnor.es\/","logo":{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/carlosoconnor.es\/#\/schema\/logo\/image\/","url":"https:\/\/carlosoconnor.es\/wp-content\/uploads\/2025\/07\/cropped-logo-wide.png","contentUrl":"https:\/\/carlosoconnor.es\/wp-content\/uploads\/2025\/07\/cropped-logo-wide.png","width":241,"height":50,"caption":"Carlos O'Connor"},"image":{"@id":"https:\/\/carlosoconnor.es\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/carlosoconnor.es\/#\/schema\/person\/c879dbc2b732eaa32429f50dfbd0a949","name":"gestion","sameAs":["https:\/\/www.ycomieronperdices.net\/temp\/oconnor2025"],"url":"https:\/\/carlosoconnor.es\/en\/author\/gestion\/"}]}},"_links":{"self":[{"href":"https:\/\/carlosoconnor.es\/en\/wp-json\/wp\/v2\/posts\/63535","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/carlosoconnor.es\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/carlosoconnor.es\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/carlosoconnor.es\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/carlosoconnor.es\/en\/wp-json\/wp\/v2\/comments?post=63535"}],"version-history":[{"count":1,"href":"https:\/\/carlosoconnor.es\/en\/wp-json\/wp\/v2\/posts\/63535\/revisions"}],"predecessor-version":[{"id":63537,"href":"https:\/\/carlosoconnor.es\/en\/wp-json\/wp\/v2\/posts\/63535\/revisions\/63537"}],"wp:attachment":[{"href":"https:\/\/carlosoconnor.es\/en\/wp-json\/wp\/v2\/media?parent=63535"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/carlosoconnor.es\/en\/wp-json\/wp\/v2\/categories?post=63535"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/carlosoconnor.es\/en\/wp-json\/wp\/v2\/tags?post=63535"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}